Course Code: BME356

Synopsis

This course applies computational methods to understand the function of genes and proteins. There is also an overview of methods to measure gene expression, and mapping of protein structures and functions. Topics include the methods for analysing gene expression, basic concepts and techniques of protein analysis, mutational analysis and their role in life.
Level: 3
Credit Units: 5
Presentation Pattern: EVERY JULY

Topics

  • Gene Expression
  • Case Studies for Gene Expression
  • Sequencing Methods
  • Applications of Protein Structure vs Sequence - Ni-binding antibodies
  • Protein Analysis and Purification
  • Case Studies for Protein Analysis and Purification
  • Protein Structure
  • Protein Modelling
  • Measuring Protein-protein interactions
  • Personalised Medicine
  • Human Genome Project
  • Mutations, Viruses

Learning Outcome

  • Examine gene expression methods and the use of computational approaches to gene expression measurement
  • Apply the principles of molecular biology to evaluate the computational methods in sequence analysis
  • Illustrate the basic concepts of protein analysis and proteonomics
  • Predict protein structure by applying computational tools
  • Analyze mutations by applying sequence and structural analysis
  • Discuss the limitation and impact of phylogenetics trees and mutations
Part-time Programmes / CET Courses