Singapore University of Social Sciences

Advanced Biomedical Instrumentation

Advanced Biomedical Instrumentation (BME357)


This course covers aspects of the concepts of biomedical engineering design used in the design of biomedical instruments. Topics include fit-for-purpose, meeting regulatory requirements and design specifications.

Level: 3
Credit Units: 5
Presentation Pattern: Every January


  • Generation and Acquisition of Electrocardiogram
  • Signal Processing of Electrocardiograms
  • Digital Filtering
  • QRS Complex Detection
  • ECG Signal Analysis in Different Domains
  • Heart Rate Variability
  • Analysis of HRV
  • Statistical Analysis
  • Ultrasound Imaging
  • Generation of MRI signal
  • Detection of MRI signal
  • Defibrillator and Pacemakers

Learning Outcome

  • Illustrate the generation and acquisition of electrocardiogram (ECG)
  • Analyze the ECG in time domain, frequency domain and by non-linear method
  • Design data mining techniques for the analysis of cardiac arrhythmia
  • Evaluate how the ECG changes in different disease subjects
  • Examine how the MRI and Ultrasound can be used to image the heart and other vascular system
  • Evaluate the different types of defibrillators and pacemakers
  • Apply the concept of spectral estimation using MATLAB
  • Demonstrate the required skills in Biomedical instrumentation, signal processing and data mining techniques
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